Listy klinické logopedie 2024, 8(1):53-59 | DOI: 10.36833/lkl.2024.0141013
Exercise-induced Laryngeal Obstruction
- MUDr. Barbora Kalendová, MUDr. Jiří Dostal, Centrum sportovní medicíny, Sokolská 1662/35, 120 00 Praha 2, Česká republika, E-mail: kalendova@centrumsportmed.cz.
Exercise-induced laryngeal obstruction (EILO) is a common cause of exertional dyspnoea occurring at maximal exertion in individuals with normal laryngeal morphology and function at rest. It is most frequent in adolescent females and in sports with high ventilation demands. The obstruction results from the adduction of laryngeal structures during inhalation, occurring either at the level of the glottis with paradoxical vocal fold movement, or more commonly with supraglottic adduction and inward prolapse of aryepiglottic folds and surrounding structures. It is often mistaken for asthma-related dyspnoea.
Keywords: exercise-induced laryngeal obstruction, exertional dyspnoea, exercise-induced bronchoconstriction, continuous laryngoscopy during exercise
Received: March 14, 2024; Revised: April 29, 2024; Accepted: May 8, 2024; Published: June 14, 2024 Show citation
References
- BEATY, M. M., WILSON, J. S., SMITH, R. J., 1999. Laryngeal motion during exercise. The Laryngoscope. [online]. 109(1), s. 136-139. DOI: 10.1097/00005537-199901000-00026. Dostupné z: Laryngeal motion during exercise - PubMed (nih.gov).
Go to original source...
Go to PubMed...
- BHATIA R., ABU-HASAN M., WEINBERGER M., 2019. Exercise-Induced Dyspnea in Children and Adolescents: Differential Diagnosis. Pediatric Annals. [online]. 48(3), s. e121-e127. DOI: 10.3928/19382359-20190219-02. Dostupné z: Exercise-Induced Dyspnea in Children and Adolescents: Differential Diagnosis | Pediatric Annals (healio.com).
Go to original source...
Go to PubMed...
- BRANCATISANO A., DODD, D. S., ENGEL, L. A., 1991. Posterior cricoarytenoid activity and glottic size during hyperpnea in humans. Journal of Applied Physiology. [online]. 71(3), s. 977-982. DOI: 10.1152/jappl.1991.71.3.977. Dostupné z: Posterior cricoarytenoid activity and glottic size during hyperpnea in humans | Journal of Applied Physiology.
Go to original source...
Go to PubMed...
- CAMPISI, E. S., SCHNEIDERMAN, J. E., OWEN, B., MORAES, T. J., CAMPISI, P., 2019. Exercise-induced laryngeal obstruction: Quality initiative to improve assessment and management. International Journal of Pediatric Otorhinolaryngology. [online]. 127. DOI: 10.1016/j.ijporl.2019.109677. Dostupné z: Exercise-induced laryngeal obstruction: Quality initiative to improve assessment and management - PubMed (nih.gov).
Go to original source...
- CLEMM, H., OLIN, J. T., MCINTOSH, C., SCHWELLNUS, M., SEWRY, N., HULL, J. H., HALVORSEN, T., 2022. Exercise-induced laryngeal obstruction (EILO) in athletes: a narrative review by a subgroup of the IOC Consensus on 'acute respiratory illness in the athlete'. British Journal of Sports Medicine. [online]. 56(11), s. 622-629. DOI: 10.1136/bjsports-2021-104704. Dostupné z: Exercise-induced laryngeal obstruction (EILO) in athletes: a narrative review by a subgroup of the IOC Consensus on 'acute respiratory illness in the athlete' - PubMed (nih.gov).
Go to original source...
Go to PubMed...
- CLEMM, H., RØKSUND, O. D., ANDERSEN, T., HEIMDAL, J. H., KARLSEN, T., HILLAND, M., FRETHEIM-KELLY, Z., HUFTHAMMER, K. O., SANDNES, A., HJELLE, S., VOLLSÆTER, M., HALVORSEN, T., Bergen ILO-group, 2022. Exercise-induced Laryngeal Obstruction: Protocol for a Randomized Controlled Treatment Trial. Frontiers in pediatrics. [online]. 10, s. 817003. DOI: 10.3389/fped.2022.817003. Dostupné z: Exercise-induced Laryngeal Obstruction: Protocol for a Randomized Controlled Treatment Trial - PubMed (nih.gov).
Go to original source...
Go to PubMed...
- DÖLLINGER, M. et al., 2023. Computational fluid dynamics of upper airway aerodynamics for exercise-induced laryngeal obstruction: A feasibility study. Laryngoscope Investigative Otolaryngology. [online]. 8(5), s. 1294-1303. DOI: 10.1002/lio2.1140. Dostupné z: Computational fluid dynamics of upper airway aerodynamics for exercise-induced laryngeal obstruction: A feasibility study - PubMed (nih.gov).
Go to original source...
Go to PubMed...
- DOMER, A. S., KUHN, M. A., BELAFSKY, P. C., 2013. Neurophysiology and clinical implications of the laryngeal adductor reflex. Current Otorhinolaryngol Reports. [online]. 1, s. 178-182. Dostupné z: Neurophysiology and Clinical Implications of the Laryngeal Adductor Reflex | Current Otorhinolaryngology Reports (springer.com).
Go to original source...
Go to PubMed...
- GRIFFIN, S. A., WALSTED, E. S., HULL, J. H., 2018. Breathless athlete: exercise-induced laryngeal obstruction. British Journal of Sports Medicine. [online]. 52(18), s. 1211-1212. DOI: 10.1136/bjsports-2018-099159. Dostupné z: Breathless athlete: exercise-induced laryngeal obstruction | British Journal of Sports Medicine (bmj.com).
Go to original source...
Go to PubMed...
- HALVORSEN, T., WALSTED, E. S., BUCCA, C., BUSH, A., CANTARELLA, G., FRIEDRICH, G. et al., 2017. Inducible laryngeal obstruction: an official joint European Respiratory Society and European Laryngological Society statement. The European Respiratory Journal. [online]. 50(3), s. 1602221. DOI: 10.1183/13993003.02221-2016. Dostupné z: Inducible laryngeal obstruction: an official joint European Respiratory Society and European Laryngological Society statement - PubMed (nih.gov).
Go to original source...
Go to PubMed...
- HALVORSEN, T., CLEMM, H. S. H., VOLLSÆTER, M. et al., 2020. Conundrums of Exercise-related breathing problems. epiglottic, laryngeal, or bronchial obstruction? American journal of respiratory and critical care medicine. [online]. 202(10), s. e142-e143. DOI: 10.1164/rccm.201910-1921IM. Dostupné z: Conundrums of Exercise-related Breathing Problems. Epiglottic, Laryngeal, or Bronchial Obstruction? - PubMed (nih.gov)
Go to original source...
Go to PubMed...
- HEIMDAL, J. H., RØKSUND, O. D., HALVORSEN, T., SKADBERG, B. T., OLOFSSON, J., 2006. Continuous laryngoscopy exercise test: a method for visualizing laryngeal dysfunction during exercise. Laryngoscope. [online]. 116(1), s. 52-57. DOI: 10.1097/01.mlg.0000184528.16229.ba. Dostupné z: Continuous laryngoscopy exercise test: a method for visualizing laryngeal dysfunction during exercise - PubMed (nih.gov).
Go to original source...
Go to PubMed...
- HILLAND, M., RØKSUND, O. D., SANDVIK, L., HAALAND, O., AARSTAD, H. J., HALVORSEN, T. et al., 2016. Congenital laryngomalacia is related to exercise-induced laryngeal obstruction in adolescence. Archives of disease in childhood. [online]. 101(5):, s. 443-448. DOI: 10.1136/archdischild-2015-308450. Dostupné z: Congenital laryngomalacia is related to exercise-induced laryngeal obstruction in adolescence - PubMed (nih.gov).
Go to original source...
Go to PubMed...
- HOCEVAR-BOLTEZAR, I., KRIVEC, U., SEREG-BAHAR, M., 2017. Laryngeal sensitivity testing in youth with exercise-inducible laryngeal obstruction. International journal of rehabilitation research. [online]. 40(2), s. 146-151. DOI: 10.1097/MRR.0000000000000222. Dostupné z: Laryngeal sensitivity testing in youth with exercise-inducible laryngeal obstruction - PubMed (nih.gov).
Go to original source...
Go to PubMed...
- HULL, J. H., GODBOUT, K., BOULET, L. P., 202. Exercise-associated dyspnea and stridor: thinking beyond asthma. The journal of allergy and clinical immunology. In practice. [online]. 8(7), s. 2202-2208. DOI: 10.1016/j.jaip.2020.01.057. Dostupné z: Exercise-Associated Dyspnea and Stridor: Thinking Beyond Asthma - PubMed (nih.gov).
Go to original source...
- HURBIS, C. G., SCHILD, J. A., 1991. Laryngeal Changes during Exercise and Exercise-Induced Asthma. Annals of Otology, Rhinology & Laryngology. [online]. 100(1), s. 34-37. DOI: 10.1177/000348949110000106. Dostupné z: Laryngeal Changes during Exercise and Exercise-Induced Asthma - Charles G. Hurbis, Joyce A. Schild, 1991 (sagepub.com).
Go to original source...
Go to PubMed...
- CHRISTENSEN, P. M., HEIMDAL, J. H., CHRISTOPHER, K. L. et al., 2015. ERS/ELS/ACCP 2013 international consensus conference nomenclature on inducible laryngeal obstructions. European Respiratory Review. [online]. 24, s. 445-450. DOI: 10.1183/16000617.00006513. Dostupné z: ERS/ELS/ACCP 2013 international consensus conference nomenclature on inducible laryngeal obstructions | European Respiratory Society (ersjournals.com).
Go to original source...
Go to PubMed...
- JOHANSSON, H., NORLANDER, K., BERGLUND, L. et al., 2015. Prevalence of exercise-induced bronchoconstriction and exercise-induced laryngeal obstruction in a general adolescent population. Thorax. [online]. 70(1), s. 57-63. DOI: 10.1136/thoraxjnl-2014-205738. Dostupné z: Prevalence of exercise-induced bronchoconstriction and exercise-induced laryngeal obstruction in a general adolescent population - PubMed (nih.gov).
Go to original source...
Go to PubMed...
- KAPRELI, E., VOURAZANIS, E., STRIMPAKOS, N., 2008. Neck pain causes respiratory dysfunction. Medical Hypotheses. [online]. 70(5), s. 1009-1013. DOI: 10.1016/j.mehy.2007.07.050. Dostupné z: Neck pain causes respiratory dysfunction - PubMed (nih.gov).
Go to original source...
Go to PubMed...
- NIELSEN, E. W., HULL, J. H., BACKER. V., 2013. High prevalence of exercise-induced laryngeal obstruction in athletes. Medicine & Science in Sports & Exercise. [online]. 45(11), s. 2030-2035. DOI: 10.1249/MSS.0b013e318298b19a. Dostupné z: High Prevalence of Exercise-Induced Laryngeal Obstruction in... : Medicine & Science in Sports & Exercise (lww.com).
Go to original source...
Go to PubMed...
- NORLANDER, K. JOHANSSON, H., JANSSON. C. et al., 2015. Surgical treatment is effective in severe cases of exercise-induced laryngeal obstruction: a follow-up study. Acta oto-laryngologica. [online]. 135(11), s. 1152-1159. DOI: 10.3109/00016489.2015.1062548. Dostupné z: Surgical treatment is effective in severe cases of exercise-induced laryngeal obstruction: A follow-up study - PubMed (nih.gov).
Go to original source...
Go to PubMed...
- NORLANDER, K., JOHANSSON, H., EMTNER, M., JANSON, C., NORDVALL, L., NORDANG. L., 2020. Differences in laryngeal movements during exercise in healthy and dyspnoeic adolescents. International journal of pediatric otorhinolaryngology. [online]. 129, s. 109765. DOI: 10.1016/j.ijporl.2019.109765. Dostupné z: Differences in laryngeal movements during exercise in healthy and dyspnoeic adolescents - PubMed (nih.gov).
Go to original source...
Go to PubMed...
- OLIN, J. T., DEARDORFF, E. H., FAN, E. M., JOHNSTON, K. L., KEEVER, V. L., MOORE, C. M. et al., 2017. Therapeutic laryngoscopy during exercise: a novel non-surgical therapy for refractory EILO. Pediatric Pulmonology. [online]. 52(6), s. 813-819. DOI: 10.1002/ppul.23634. Dostupné z: Therapeutic laryngoscopy during exercise: A novel non-surgical therapy for refractory EILO - Olin - 2017 - Pediatric Pulmonology - Wiley Online Library.
Go to original source...
Go to PubMed...
- PARGETER, N. J., MANSUR, A. H., 2007. The relationship between gastro-oesophageal reflux and vocal cord dysfunction in a clinical setting. Thorax. [online]. 62. Dostupné z: The relationship between gastro-oesophageal reflux and vocal cord dysfunction in a clinical setting | Request PDF (researchgate.net).
- PERKNER, J. J., FENNELLY, K. P., BALKISSOON, R., BARTELSON, B. B., RUTTENBER, A. J., WOOD, R. P. et al., 1998. Irritant-associated vocal cord dysfunction. Journal of occupational and environmental medicine. [online]. 40(2). s. 136-143. DOI: 10.1097/00043764-199802000-00009. Dostupné z: Irritant-associated vocal cord dysfunction - PubMed (nih.gov).
Go to original source...
Go to PubMed...
- PETCU, L. G, SASAKI, C. T., 1991. Laryngeal anatomy and physiology. Clinics in Chest Medicine. [online]. 12(3), s. 415-423. DOI: 10.1016/S0272-5231(21)00793-0. Dostupné z: Laryngeal Anatomy and Physiology - Clinics in Chest Medicine (theclinics.com).
Go to original source...
- PHUA, S. Y., McGARVEY, L., NGU, M., ING, A., 2010. The differential effect of gastroesophageal reflux disease on mechanostimulation and chemostimulation of the laryngopharynx. Chest. [online]. 138(5), s. 1180-1185. DOI: 10.1378/chest.09-2387. Dostupné z: The differential effect of gastroesophageal reflux disease on mechanostimulation and chemostimulation of the laryngopharynx - PubMed (nih.gov).
Go to original source...
Go to PubMed...
- PIANOSI, P. T., ORBELO, D. M., COFER, S. A., 2018. Observational study of laryngoscopy plus flow-volume loops during exercise. Clinical case reports. [online]. 6(4), s. 735-740. DOI: 10.1002/ccr3.1375. Dostupné z: Observational study of laryngoscopy plus flow-volume loops during exercise - PubMed (nih.gov).
Go to original source...
Go to PubMed...
- RØKSUND, O. D. et al., 2009. Exercise induced dyspnea in the young. Larynx as the bottleneck of the airways. Respiratory Medicine. [online]. 103(12), s. 1911-1918. DOI: 10.1016/j.rmed.2009.05.024. Dostupné z: Exercise induced dyspnea in the young. Larynx as the bottleneck of the airways - ScienceDirect.
Go to original source...
Go to PubMed...
- RØKSUND, O. D., HEIMDAL, J. H., OLOFSSON J., MAAT, R. C., HALVORSEN, T., 2015. Larynx during exercise: the unexplored bottleneck of the airways. European Archives of Oto-Rhino-Laryngology. [online]. 272(9), s. 2101-2109. DOI: 10.1007/s00405-014-3159-3. Dostupné z: Larynx during exercise: the unexplored bottleneck of the airways | European Archives of Oto-Rhino-Laryngology (springer.com).
Go to original source...
Go to PubMed...
- RØKSUND, O. D, HEIMDAL, J. H., CLEMM, H., VOLLSÆTER, M., HALVORSEN, T., 2017. Exercise inducible laryngeal obstruction: diagnostics and management. Paediatric respiratory reviews. [online]. 21, s. 86-94. DOI: 10.1016/j.prrv.2016.07.003. Dostupné z: Exercise inducible laryngeal obstruction: diagnostics and management - PubMed (nih.gov).
Go to original source...
Go to PubMed...
- SANDNES, A., ANDERSEN, T., CLEMM, H. H., HILLAND, M., VOLLSÆTER, M., HEIMDAL, J. H., EIDE, G. E., HALVORSEN, T., RØKSUND, O. D., 2019. Exercise-induced laryngeal obstruction in athletes treated with inspiratory muscle training. BMJ Open Sport & Exercise Medicine. [online]. 5(1), s. e000436. DOI: 10.1136/bmjsem-2018-000436. Dostupné z: e000436.full.pdf (bmj.com).
Go to original source...
Go to PubMed...
- SANDNES A., ANDERSEN, T., CLEMM, H. H., HILLAND, M., HEIMDAL, J. H., HALVORSEN, T., RØKSUND, O. D., VOLLSÆTER, M., 2022. Clinical responses following inspiratory muscle training in exercise-induced laryngeal obstruction. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS). [online]. 279(5), s. 2511-2522. DOI: 10.1007/s00405-021-07214-5. Dostupné z: Clinical responses following inspiratory muscle training in exercise-induced laryngeal obstruction - PubMed (nih.gov).
Go to original source...
Go to PubMed...
- SIEWERS K., BACKER, V., WALSTED, E. S., 2019. A systematic review of surgical treatment for supraglottic exercise-induced laryngeal obstruction. Laryngoscope Investigative Otolaryngology. 4(2), s. 227-233. DOI: 10.1002/lio2.257. Dostupné z: A systematic review of surgical treatment for supraglottic exercise-induced laryngeal obstruction - PubMed (nih.gov).
Go to original source...
Go to PubMed...
- TERVONEN, H., NISKANEN, M. M., SOVIJÄRVI, A. R., HAKULINEN, A. S., VILKMAN, E. A., AALTONEN, L. M., 2009. Fiberoptic videolaryngoscopy during bicycle ergometry: a diagnostic tool for exercise-induced vocal cord dysfunction. Laryngoscope. [online]. 119(9), s. 1776-1180. DOI: 10.1002/lary.20558. Dostupné z: Fiberoptic videolaryngoscopy during bicycle ergometry: A diagnostic tool for exercise-induced vocal cord dysfunction - Tervonen - 2009 - The Laryngoscope - Wiley Online Library.
Go to original source...
Go to PubMed...
- VAN HOUTTE, E., VAN LIERDE, K., CLAEYS, S., 2011. Pathophysiology and treatment of muscle tension dysphonia: a review of the current knowledge. Journal of voice : official journal of the Voice Foundation. [online]. 25(2), s. 202-207. DOI: 10.1016/j.jvoice.2009.10.009. Dostupné z: Pathophysiology and treatment of muscle tension dysphonia: a review of the current knowledge - PubMed (nih.gov).
Go to original source...
Go to PubMed...
- VOLLSÆTER, M., STENSRUD, T., MAAT, R., HALVORSEN, T., RØKSUND, O. D., SANDNES, A., CLEMM. H., 2022. Exercise Related Respiratory Problems in the Young - Is It Exercise-Induced Bronchoconstriction or Laryngeal Obstruction? Frontiers in Pediatrics. [online]. 9, s. 800073. DOI: 10.3389/fped.2021.800073. Dostupné z: Frontiers | Exercise Related Respiratory Problems in the Young-Is It Exercise-Induced Bronchoconstriction or Laryngeal Obstruction? (frontiersin.org).
Go to original source...
Go to PubMed...
- WALSTED, E. S., FAMOKUNWA, B., ANDERSEN, L. et al., 2021. Characteristics and impact of exercise-induced laryngeal obstruction: an international perspective. ERJ Open Research. [online]. 7(2), s. 00195-02021. DOI: 10.1183/23120541.00195-2021. Dostupné z: Characteristics and impact of exercise-induced laryngeal obstruction: an international perspective - PubMed (nih.gov).
Go to original source...
Go to PubMed...
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